Allergy Frontiers PDF
by Stephen T. Holgate
The prevalence of allergic diseases and asthma are on the rise in industrialized as well as industrializing countries with a marked impact on the quality of life of patients and a socioeconomic impact to the countries. This book summarizes the most current knowledge on allergic diseases from epidemiology to mechanisms, environmental and genetic factors that influence the development of allergy and asthma clinical aspects, recent therapeutic and preventive strategies as well as future perspectives. The several chapters also highlight the role of eosinophils, mast cells, lymphocytes, dendritic cells, epithelial cells, neutrophils and T cells, adhesion molecules and cytokines/ chemokines in the pathomechanisms of allergic diseases. Also discussed are the impact of infection and innate immunity on allergy, and mucosal immunology of the various target organs and allergy. Among the therapeutic strategies we have included most recent and emerging therapies including allergen-specific immunotherapy and anti-IgE treatment.. The multidisciplinary character of this book is documented by articles from various fields such as environmental, molecular, and cellular biology, allergy, otolaryngology, pulmonology and dermatology. Representing an excellent collection of state-of-the art reviews by world known leaders from the UK, Europe, North America, South America, Australia, Japan and South Africa, this comprehensive and up-to-date book on allergy and clinical immunology contains over 200 chapters covering virtually all aspects of basic and clinical allergy. Comprising of 6 volumes with each volume dedicated to a specific aspect of allergic disease [Volume 1: Evolution of Allergy, Epigenetics and Phenotypes, Allergens and Risk factors; Volume 2: Classification and Pathomechanisms, Allergy and the Nervous system and Allergy and mucosal immunology; VOLUME 3: Clinical manifestation of allergic diseases; Volume 4: Diagnosis and DD of allergic diseases and Allergy and Asthma Education; Volume 5: Therapy and prevention of allergies and Special Considerations in Children, Elderly and Pregnancy; Volume 6: Future perspectives], it is well illustrated throughout with numerous schematic diagrams and colour illustrations, and will serve as a valuable tool of information for scientists and practical guide for clinicians working in the field of allergy, asthma and immunology.
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